Best Medical Billing Software

Heidi AI is an AI-powered healthcare assistant designed to reduce the administrative burden on clinicians and care teams. Built for modern clinical practice, Heidi AI helps healthcare professionals capture patient notes, streamline follow-ups, support patient communications, and access clinical evidence when making decisions. Its suite of products includes Scribe for documentation, Comms for office administration, Evidence for on-demand medical information, and Remote for mobile, in-room note capture. This makes it especially useful for family medicine, specialists, nurses, mental health providers, allied health professionals, dentists, veterinarians, and trainees. By automating repetitive tasks across the care journey, Heidi AI helps practices save time, improve documentation quality, and keep workflows moving from first visit to final follow-up. It is also built with strong healthcare compliance standards in mind, making it a compelling choice for clinics, practices, and enterprise health organizations that want to improve efficiency without sacrificing security or the quality of care. Read Heidi AI Reviews

Waystar is a cloud-based revenue cycle management platform used by healthcare providers of many sizes to manage the full billing lifecycle in one system, from financial clearance and eligibility verification through claims, payment posting, denial management, and analytics. Its AltitudeAI technology is built into the platform to automate tasks such as prior authorization tracking, patient estimation, and claim error prevention, and it integrates with a practice's existing EHR or practice management system.

Waystar does not publish fixed pricing plans or a public price list. Organizations request a demo and receive a custom quote based on provider count, transaction volume, and which modules they select, such as denial prevention, analytics, or claim attachment tools. Separate implementation and integration costs may also apply.

Medisoft, now branded CGM MEDISOFT, is a practice management and billing software originally developed by McKesson and now owned and sold by CompuGroup Medical (CGM), a German health IT company with a large US healthcare division. It targets small to mid-sized medical practices and combines scheduling, claims and statement management, reporting, and an OCR insurance card scanner, with the option to pair it with CGM's APRIMA EHR for a fuller clinical and administrative system.

CGM does not publish pricing on its official product page; practices are directed to a network of value-added resellers for quotes and support. Resellers have historically offered Medisoft as either a one-time perpetual license or a tiered cloud subscription, but exact current pricing is not confirmed on CGM's own site, so figures should be verified directly with a reseller.

EZClaim is a medical billing and scheduling practice management system aimed at small to mid sized provider offices and independent billing companies, and can be deployed on premises or in the cloud. Core features include electronic 837 claim submission, eligibility verification, customizable superbills and patient statements, drag and drop scheduling with authorization tracking, electronic remittance advice, and EZClaimPay for integrated credit and debit card processing.

Pricing is per user: the monthly plan costs $199 for the first user and $149 for each additional user, while paying annually lowers those rates to $189 and $144 per month respectively. Add ons include extra company files, additional cloud storage, read only EZClaim Portal access, and support for a second product, and clearinghouse fees apply separately. No long term contract is required, and support is included through onboarding coaching, online resources, and live assistance.

PracticeSuite is a cloud-based practice management, EHR, and medical billing platform based in Tampa, Florida, aimed at medical practices and third-party billing companies of various sizes. It offers modular solutions spanning billing, EHR, scheduling, and patient engagement so customers can choose only the components they need, along with tools like patient kiosks, CRM-style patient outreach, and telehealth.

The company does not publish standard pricing tiers. Instead, it builds a custom package and quote based on a practice's specialty, provider count, and required modules, offering both per-provider and per-transaction pricing models. Prospective customers must book a demo or contact sales to receive exact pricing.

Office Ally is a web based healthcare technology company offering a no cost practice management system called Practice Mate, a clearinghouse called Service Center that connects to more than 5,000 payers, and a separately priced cloud EHR called EHR 24/7. Practice Mate covers appointment scheduling, patient billing, superbills, patient ledgers, and reporting at no monthly charge, though transaction based fees apply for certain claims and optional add on services such as eligibility checks, patient reminders, and secure messaging.

EHR 24/7 costs $44.95 per provider per month and adds clinical charting, configurable SOAP notes, lab and HIE interfacing, and document management. Larger organizations needing dedicated EDI clearinghouse or payer gateway access can request custom enterprise pricing. This combination of free core tools and pay as you grow add ons makes Office Ally a common choice for small and mid sized medical, dental, and behavioral health practices.

CGM Lytec is a practice management and EHR system for medical offices, developed by CompuGroup Medical and sold through an authorized reseller network rather than directly. It provides scheduling with online booking and waitlists, patient search by insurance ID, charge entry, and billing tools built to speed up claim submission and reimbursement. The software integrates with the eMEDIX clearinghouse for claims and eligibility, and can pair with CGM APRIMA EHR for a combined clinical and administrative workflow. CGM Pay adds PCI compliant payment processing with QR code enabled patient statements.

Lytec is available as a traditional on premises Windows application or as Lytec Cloud, a hosted version offering remote access, automatic backups, and simplified budgeting. Because pricing is set by individual resellers rather than published by CGM, practices must request a quote directly. New feature releases arrive annually, most recently CGM Lytec 2026, which added mobile friendly patient responsibility estimates and expanded clearinghouse integration.

NueMD is a cloud based practice management, medical billing, and EHR platform originally built by NueSoft and later owned by AdvancedMD. It bundles ONC-ATCB certified charting, e-prescribing, lab report tracking, and secure fax with a built in HIPAA compliant clearinghouse that has historically processed millions of claims annually. Scheduling tools track patients from arrival to departure, send appointment reminders, and sync to mobile devices, and the platform includes iOS and Android apps alongside integrated credit card processing.

AdvancedMD has announced that it will retire NueMD and end all support for the platform by December 31, 2026, migrating existing clients to AdvancedMD's own system as part of a planned transition described as low disruption. Because of this wind down, NueMD is not a viable long term choice for new customers, and official pricing is no longer published on its website, which now redirects visitors directly to AdvancedMD's migration information page.

Availity operates one of the largest real time health information networks in the United States, connecting more than a million providers with over 2,700 payers for eligibility and benefits checks, prior authorizations, referrals, claim submission, claim status, and remittance. Its free Essentials portal gives providers no cost access to sponsored payer transactions, while Essentials Plus is a paid subscription tier that unlocks transactions with additional, non sponsored health plans beyond what the free tier supports.

Availity also offers EDI clearinghouse and payer gateway products for higher volume electronic transaction needs, along with AI enabled workflow tools aimed at reducing administrative burden for both providers and payers. Exact subscription pricing for Essentials Plus and clearinghouse services is not published on Availity's website; prospective customers must request information directly, so practices should confirm current rates with an Availity representative before committing.

RXNT is a cloud-based healthcare software company, founded in Maryland in 1999, that offers electronic health records, e-prescribing, practice management, medical billing, and scheduling as either standalone modules or an integrated Full Suite. It targets practices of varying sizes, including billing companies and hospice organizations, and emphasizes transparent, published pricing rather than requiring a sales quote for most products.

Its practice management system uses two-level claim scrubbing to help prevent rejections, while its EHR includes customizable encounter forms, AI-powered ambient listening, and telehealth through VideoBridge. RXNT includes onboarding, training, data import, and in-house support at no extra charge, and offers a 10% discount for annual billing versus monthly billing.