OpenEvidence

OpenEvidence is an AI copilot for doctors that helps them make high-stakes decisions at the point of care, and the company states it has become the default operating system of medical knowledge in the United States in a remarkably short period.

Its content licensing is the substantive differentiator and is unusually specific. OpenEvidence content includes figures, tables, multimedia and full-text clinical findings from The New England Journal of Medicine, from JAMA and the JAMA Network specialty journals, and from Nature and the Nature Portfolio.

Full-text licensing from those three matters enormously for clinical AI. Most systems are trained on or retrieve from abstracts and open access material, which means the actual results tables, the figures and the methodological detail are absent, and those are precisely where a clinical finding is qualified. An AI answering from the full paper including its figures and tables is working from what a doctor would read, rather than from a summary of it.

Licensing rather than scraping also resolves the copyright question that hangs over much of this field, which matters for an institution deciding whether the tool is defensible to deploy. The positioning as a copilot for high-stakes decisions at the point of care is appropriately narrow, addressing the moment of clinical uncertainty rather than general medical education. Pricing is not published on the captured page.